Key Hormones That Could Be Sabotaging Your Weight Loss Efforts

It’s a new year and the new you wants to lose some unwanted nagging pounds, but you’re over 40 and you just can’t lose it as fast as you used to. Time spent in the gym may or may not be fruitful, depending on how your body responds to the physical stress you’re putting yourself through.

As we get older, our body does not respond the same way to the routine we used to have in managing weight. Everything changes, including the hormones that helped us to stay trim and fit; they don’t work as they should or there’s just not enough of them. There are some key hormones you need to keep in mind if you want to lose weight and keep it off after 40.

Estrogen and Progesterone Imbalance

When the amount of estrogen in the body outweighs the levels of its hormonal counterpart, progesterone, both sexes are at greater risk for obesity. This imbalance between estrogen and progesterone is commonly referred to as estrogen dominance. Excess estrogen, a female sex hormone, can result from exposure to xenoestrogens (compounds that dress themselves up like estrogen once they enter the body). These estrogen imposters are found in pesticides, meat and dairy products produced using growth hormones, plastics that contain phalates, and skin products containing parabens. Excessive alcohol use and/or a high fat diet can also cause estrogen to accumulate in the body. The number one trigger for estrogen imbalance is obesity. The heavier you are, the more estrogen your fat cells produce. This estrogen imbalance can put you at risk for hormone-dependent cancers like breast and uterine cancer.

When women go through peri-menopause, their estrogen levels start to drop, and by menopause, the levels plummet. This probably explains why 30% of women between the ages of 50 and 59 are obese. There appears to be a connection between estrogen and body weight regulation. Lower estrogen levels may slow down your metabolic rate. An imbalance in estrogen levels — too high or too low — appear to lead to fat storage.

Progesterone and estrogen both play a role in keeping women’s waists smaller. This is because estrogen works against the action of insulin while both estrogen and progesterone oppose the action of cortisol (our stress hormone). Progesterone together with estrogen halts the storage of fat around the waist, but stress can sometimes have a negative impact on progesterone’s action. If you see fat accumulating around your belly, it could be that your body is so stressed out that it’s converting any progesterone you’re producing to cortisol, making you retain fat. This is seen more so in menopause.

Insulin Resistance

Insulin is a hormone that is released from the pancreas in response to a meal. Insulin processes the sugars from carbohydrates and carries them to your cells, which in turn uses the carbs for energy or stores them for later. When there is an overproduction of insulin, largely due to a diet rich in processed carbohydrates, high fructose corn syrup, or artificial sweeteners, the body stores unused sugars as fat. Over-production of insulin can lead to insulin resistance and eventually to type 2 diabetes. Too much insulin can impact weight loss by creating low blood sugar, which makes you constantly tired and hungry.

Signs that your pancreas is in insulin production overdrive include excess belly fat, constant hunger and cravings, water retention, high cholesterol, and high blood pressure. In addition, other symptoms include poor concentration, anxiety, fatigue, and irritability. These symptoms should sound familiar, similar to what you would experience after a high carb crash.

Thyroid

Hypothyroidism, or low thyroid, affects 10 – 20% of Americans. Some classic symptoms include unexplained weight gain, fatigue, and depression. T4 and T3 are two thyroid hormones that affect metabolism. Low levels, or an inability to convert the inactive T4 to T3, can slow metabolism. Thyroid dysfunction and imbalance in these hormones can be hereditary. However, diet, menopause, stress, and other factors can also have an impact.

Many may not know that estrogen and progesterone can affect proper thyroid functioning. The delicate balance between estrogen and progesterone is critical for a woman’s overall health and balance. Unfortunately, progesterone levels begin to drop more quickly in women in their late thirties, leaving estrogen unopposed and creating an imbalance called estrogen dominance. Estrogen dominance causes the liver to produce high levels of a protein that binds thyroid hormone and decreases the amount of thyroid hormone that can be used by cells.

Androgens

Testosterone and DHEA-S (dehydroepiandrosterone sulfate) are hormones called androgens, the “male” reproductive hormones. These hormones, in men, decline with age, thereby impacting metabolism. In women, excess androgen hormones can lead to insulin resistance, which can affect weight loss. A deficiency in women can also cause decreased metabolism, making it difficult to lose weight.

DHEA-S helps to support stress; without it, we feel worn out and unmotivated, especially for working out. Testosterone and DHEA-S help to increase muscle mass and build bone. Declining levels of testosterone can lead to more belly fat.

Cortisol

Last but not least, the 21st century’s number one enemy — the chronically high stress hormone cortisol — is a major culprit in weight gain and stubborn belly fat. Your body needs a boost in adrenaline and cortisol for short term stressors, but in this day and age it seems as though we are in a perpetual state of cortisol overload. This state can be destructive, especially when it comes to weight loss. Too much cortisol can suppress all the hormones that help you burn fat. It can lower levels of metabolism-boosting thyroid hormones, promote the loss of muscle tissue, increase appetite-stimulating hormones, and makes you crave more carbohydrate rich comfort foods. In fact, a telltale sign of chronically high cortisol levels is stubborn belly fat. Other signs of cortisol imbalance include difficulty falling asleep, waking between 2 and 4 am, digestive problems, sugar and salt cravings, muscle tension, headaches, anxiety, and depression.

Cortisol and insulin, together with lower testosterone and estrogen levels, are all implicated in stubborn belly fat! Hormones all work together for proper functioning in the body. However, when there is disruption or dysfunction that occurs somewhere in the hormone pathway, the body becomes unbalanced and weight loss becomes virtually impossible!

What to Do

Weight loss is hard enough without fighting against your own body. Get your hormones tested if you’re a female between the ages of 35 and 55 or if you have symptoms that are suspect for hormone imbalance. Saliva and blood testing are available. A base line of your sex hormones such as estradiol, progesterone, testosterone, and DHEA-S including a thyroid panel and salivary cortisol levels can help your practitioner or compounding pharmacist specially trained in this area help you regain your balance for optimum weight management.

Eat more fiber and less processed, high carb foods to help decrease your insulin levels to decrease belly fat. Manage your stress with more sleep, yoga, pilates, walking, time with your family, and just laughing out loud! Life gets too serious, and we show it on the outside with the extra fluff we carry around, especially around the middle.

If you are struggling with weight loss and need help finding out which body systems are out of balance and contributing to your stubborn weight gain, make an appointment with our integrative and functional medicine pharmacist Zoom H. Heaton to discover the uniqueness of how your body works and which elements are impeding your weight loss efforts.

Picture of Zoom H. Heaton

Zoom H. Heaton

TLC Medical Centre pharmacy is a traditional pharmacy offering specialized services such as medical equipment, compression stocking fittings, diabetic shoes fitting with shoe selection on site, vaccinations throughout the year and medical compounding (our compounding lab is located inside TLC called Custom Prescription Compounders, LLC). Our compounding pharmacist Zoom H. Heaton is also board certified in Anti-aging, Metabolic and Functional medicine. She works with patients needing help with various medical needs such as bio-identical hormone management, adrenal and thyroid issues, autoimmune conditions, weight management, pain management compounding, nutritional guidance using specialized testing and much much more. If you feel that your health needs a change for the better, call us at 803.648.7800 extension 200 and make an appointment. The first 15 minutes of your consultation with Zoom is free.
Picture of Zoom H. Heaton

Zoom H. Heaton

TLC Medical Centre pharmacy is a traditional pharmacy offering specialized services such as medical equipment, compression stocking fittings, diabetic shoes fitting with shoe selection on site, vaccinations throughout the year and medical compounding (our compounding lab is located inside TLC called Custom Prescription Compounders, LLC). Our compounding pharmacist Zoom H. Heaton is also board certified in Anti-aging, Metabolic and Functional medicine. She works with patients needing help with various medical needs such as bio-identical hormone management, adrenal and thyroid issues, autoimmune conditions, weight management, pain management compounding, nutritional guidance using specialized testing and much much more. If you feel that your health needs a change for the better, call us at 803.648.7800 extension 200 and make an appointment. The first 15 minutes of your consultation with Zoom is free.

In the know

Related Stories

Take Action to Change Your Results | Palmetto Bella

Take Action to Change Your Results

Did you gain the “COVID-19” over the past year? It is similar to the “Freshman 15” — a number of studies show that many people did gain weight in 2020. In a poll taken by WebMD®, 50% of women and 25% of men reported they had gained weight during the pandemic lockdowns. Another survey by Weight Watchers® had similar results. About a third of the Weight Watchers respondents said they gained weight, with the average gain of 12 1/2 pounds. Another study of nearly 8000 adults was taken last April, with results published in the Journal of Obesity. Almost 28% of the total sample reported weight gain. Individually we can

Read More »
How Can LDN Help in Chronic Conditions and Pain? | Palmetto Bella

How Can LDN Help in Chronic Conditions and Pain?

Nearly half of all Americans have at least one chronic disease. Once you have one chronic disease, you have a higher risk of developing others. Inflammation seems to be at the root of all disease. What if there were a cost effective agent that could help fight inflammation, that could regulate your immune system so it doesn’t get out of hand, and that could be useful in treating major health issues like chronic pain, mental health conditions, autoimmune conditions, and even cancers? It does seem too good to be true, so let’s look at the science, and then you can decide whether this may be right for you. What is

Read More »
Love and Lemon Pound Cake | Palmetto Cake

Love and Lemon Pound Cake

I was walking through the market area in Charleston in May of 2019. As I was noticing the sweetgrass baskets, kitschy T-shirts, spice mixes, and beach treasures, I spied some bottles of extract. This was a brand that I had not often seen since childhood. There, among the many items of the market, were bottles of lemon extract. Seeing them took me back to the kitchen of my childhood home in Greensboro, North Carolina, some 45 years earlier, where that extract could be found on the spice rack. “Hi Mom! Hi Nano! I’m home from school!” I yelled to my mother and grandmother as I opened the back door that

Read More »
Childhood Obesity: Who is to blame? | Palmetto Bella

Childhood Obesity: Who is to blame?

A society must be judged by how it treats its most vulnerable members: its children. It seems that America is falling shamefully short. We know that to succeed, children need stable homes, quality health care, ample nutritious food, good schools, safe neighborhoods, and access to resources and opportunities that enable them to reach their potential. For too many of our children, especially children of color, these basic building blocks are out of reach. And yet, in the wealthiest nation on Earth, the proportion of federal dollars invested in children has fallen to its lowest level in a decade. The shameful state of your child’s health is not an inevitability —

Read More »